Ravichandran Ramasamy Selected Research

caficrestat

11/2021

A pilot open-label study of aldose reductase inhibition with AT-001 (caficrestat) in patients hospitalized for COVID-19 infection: Results from a registry-based matched-control analysis.

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Ravichandran Ramasamy Research Topics

Disease

25	Inflammation (Inflammations) 01/2022 - 12/2003
16	Ischemia 01/2017 - 02/2002
15	Hyperglycemia 04/2022 - 05/2003
13	Atherosclerosis 01/2022 - 08/2004
12	Diabetes Complications 04/2022 - 11/2003
11	Obesity 01/2021 - 09/2012
11	Reperfusion Injury 12/2017 - 08/2004
10	Cardiovascular Diseases (Cardiovascular Disease) 01/2021 - 10/2005
7	Infarction (Infarctions) 01/2017 - 04/2002
6	Myocardial Ischemia (Ischemic Heart Diseases) 12/2017 - 08/2004
6	Chronic Disease (Chronic Diseases) 01/2017 - 08/2007
4	Vascular System Injuries 01/2022 - 10/2005
4	Neoplasms (Cancer) 01/2016 - 09/2009
3	Diabetes Mellitus 11/2021 - 09/2012
3	Atherosclerotic Plaque (Atheroma) 12/2015 - 01/2008
3	Myocardial Infarction 01/2015 - 11/2003
3	Hyperlipidemias (Hyperlipidemia) 10/2013 - 08/2004
2	Type 2 Diabetes Mellitus (MODY) 04/2022 - 01/2021
2	COVID-19 11/2021 - 01/2021
2	Heart Diseases (Heart Disease) 11/2021 - 03/2009
2	Fibrosis (Cirrhosis) 01/2021 - 01/2012
2	Alzheimer Disease (Alzheimer's Disease) 03/2016 - 01/2016
2	Necrosis 07/2015 - 04/2008
2	Heart Failure 06/2012 - 01/2012
2	Renal Insufficiency (Renal Failure) 04/2012 - 09/2007
2	Hypoxia (Hypoxemia) 04/2012 - 04/2010
2	Diabetic Nephropathies (Diabetic Nephropathy) 08/2010 - 05/2003
1	Kidney Diseases (Kidney Disease) 11/2021
1	Infections 11/2021
1	Hemolysis 01/2021
1	Mitochondrial Diseases (Mitochondrial Disease) 01/2021
1	Overnutrition 01/2020
1	Metabolic Diseases (Metabolic Disease) 01/2020
1	Weight Loss (Weight Reduction) 01/2020
1	Neurodegenerative Diseases (Neurodegenerative Disease) 01/2019
1	Sclerosis 12/2018
1	Insulin Resistance 01/2016
1	Body Weight (Weight, Body) 01/2015
1	Hemorrhage 02/2014
1	Diabetic Angiopathies (Diabetic Angiopathy) 02/2014
1	Acute Coronary Syndrome 12/2013
1	Pre-Eclampsia (Preeclampsia) 10/2013

Drug/Important Bio-Agent (IBA)

30	LigandsIBA 04/2022 - 05/2003
26	Receptor for Advanced Glycation End ProductsIBA 04/2022 - 11/2003
20	Aldehyde Reductase (Aldose Reductase)IBA 11/2021 - 02/2002
14	Advanced Glycation End ProductsIBA 01/2022 - 05/2003
12	EnzymesIBA 01/2017 - 02/2002
10	Glucose (Dextrose)FDA LinkGeneric 02/2014 - 02/2002
7	polyolIBA 01/2017 - 11/2003
6	Proteins (Proteins, Gene)FDA Link 01/2020 - 12/2003
5	Biomarkers (Surrogate Marker)IBA 12/2017 - 12/2007
5	Adenosine Triphosphate (ATP)IBA 02/2013 - 02/2002
4	LipidsIBA 01/2020 - 12/2003
3	CholesterolIBA 01/2022 - 12/2015
3	Oxidants (Oxidizing Agents)IBA 01/2018 - 12/2003
3	Triglycerides (Triacylglycerol)IBA 12/2015 - 06/2005
2	SugarsIBA 01/2022 - 01/2020
2	AlbuminsIBA 12/2018 - 08/2010
2	CreatinineIBA 12/2018 - 08/2010
2	ForminsIBA 12/2017 - 05/2012
2	Messenger RNA (mRNA)IBA 12/2015 - 05/2012
2	Apolipoproteins E (ApoE)IBA 02/2014 - 01/2008
2	Doxorubicin (Adriamycin)FDA LinkGeneric 10/2013 - 05/2008
2	Reactive Oxygen Species (Oxygen Radicals)IBA 09/2012 - 04/2012
2	Insulin (Novolin)FDA Link 09/2012 - 05/2010
2	L-Iditol 2-Dehydrogenase (L Iditol 2 Dehydrogenase)IBA 09/2011 - 10/2008
2	Streptozocin (Streptozotocin)FDA Link 09/2010 - 09/2005
2	LDL Receptors (LDL Receptor)IBA 05/2010 - 09/2005
2	Amyloid beta-PeptidesIBA 01/2009 - 10/2005
2	Immunoglobulins (Immunoglobulin)IBA 04/2008 - 05/2006
2	Fatty Acids (Saturated Fatty Acids)IBA 11/2003 - 12/2002
1	Interferon Regulatory Factor-7 (Interferon Regulatory Factor 7)IBA 01/2022
1	Interleukin-6 (Interleukin 6)IBA 11/2021
1	caficrestatIBA 11/2021
1	InterferonsIBA 01/2021
1	Glucagon-Like Peptide-1 ReceptorIBA 01/2021
1	Angiotensin IIIBA 01/2021
1	Sodium-Glucose Transport ProteinsIBA 01/2021
1	Heme (Haem)IBA 01/2021
1	PlasticsIBA 01/2020
1	Netrin-1IBA 01/2019
1	CateninsIBA 01/2017
1	NexusIBA 01/2017
1	KATP ChannelsIBA 01/2016
1	ATP-Binding Cassette Transporters (ABC Transporters)IBA 12/2015
1	Amino Acids FDA Link 07/2015
1	Omega-3 Fatty Acids (Omega 3 Fatty Acids)IBA 01/2015
1	EmulsionsIBA 01/2015
1	Antigen-Antibody Complex (Immune Complex)IBA 06/2014
1	MelanocortinsIBA 06/2014
1	Carbon MonoxideIBA 12/2013
1	PEG-hemoglobinIBA 12/2013
1	PEGylated carboxyhemoglobin bovineIBA 12/2013
1	Hemoglobins (Hemoglobin)IBA 12/2013
1	Acetaminophen (Paracetamol)FDA LinkGeneric 10/2013

Therapy/Procedure

9	Therapeutics 01/2021 - 09/2003
2	Transplantation 01/2020 - 12/2008
1	Length of Stay 11/2021
1	Bariatric Surgery 01/2020
1	Lasers (Laser) 12/2015